PRF - Platelet Rich Fibrin
Platelet Rich Fibrin or PRF is a fibrin network that acts as a reservoir or tissue growth factors. These growth factors promote proliferation and differentiation of cells that are crucial for healing.
What is PRF?
PRF is Platelet Rich Fibrin. This is obtained by spinning blood in a centrifuge. This separates it into red blood cells, acellular plasma and the fibrin clot. Once the blood is separated, we collect the portion of the fibrin clot that contains the leukocytes and platelets rich in growth factors. These growth factors promote proliferation and differentiation of osteoblasts, endothelial cells, chondrocytes, and various sources of fibroblasts. Platelet Rich Fibrin (PRF) can be used as a membrane, gel, plug or mixed with bone substitutes to make ‘sticky bone’.
What is PRF used for?
PRF can be placed into extraction sockets and during bone grafting, or used with soft tissue healing. It encourages revascularisation, and thus enhances and speeds up healing and bone formation. PRF is made from the patient’s own blood so it’s very biocompatible, readily available, easy to prepare and there is no risk of a foreign body response, making it very safe.
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